XI International Meeting on Paracoccidioidomycosis

XI International Meeting on Paracoccidioidomycosis

Resume:73-8

Poster (Painel)

73-8	Occurrence of 102 paracoccidioidomycosis cases in 18 months in ਀䤀琀愀椀瀀甀䰀愀欀攀爀攀最椀漀渀Ⰰ 眀攀猀琀攀爀渀倀愀爀愀渀
Authors:	Eduardo Alexandre Loth (UNIOESTE - Universidade Estadual do Oeste do Paraná) ; Caroline Danielli (UNIOESTE - Universidade Estadual do Oeste do Paraná) ; Samia Khalil Biazin (UNIOESTE - Universidade Estadual do Oeste do Paraná) ; Joseane Rodrigues Silva (UNIOESTE - Universidade Estadual do Oeste do Paraná) ; Rinaldo Ferreira Gandra (UNIOESTE - Universidade Estadual do Oeste do Paraná)

Abstract

Introduction Paracoccidioidomycosis (PCM) is a systemic mycosis caused by the dimorphic fungus Paracoccidioides brasiliensis. It is considered the most important fungal infection in Latin America and 80% of cases occur in Brazil. The organs most affected are the lungs by PCM. Infection occurs by accidental inhalation of the pathogen by the host, which mainly infects the lungs and can spread throughout the body, causing damage to internal organs, and mucocutaneous lesions. The aim of this study was to investigate the incidence of PCM in residents of the Itaipu Lake region in the period 2008-2009. Materials and Methods: The study was conducted at the Division of Tuberculosis of the Epidemiological Surveillance Center in Foz do Iguacu, ParanÃƒÂ¡. The data were collected biweekly in medical records and records of the patients treated between January 2008 and July 2009, residents in the region of the Itaipu Lake, which includes residents of Brazil, Argentina and Paraguay. We collected data relating to personal data, number of cases, number of deaths, clinical form of disease and death rate per million inhabitants. The results showed the result set 102 new cases of PCM in the period studied. Of these, 70.6% men and 29.4% were women, showing a ratio of 2,4:1,respectively. Place of residence was recorded more frequently in urban areas, 52.9% and 11.8% lived in rural areas and 35.3% of records had contained no information. Among the clinical forms, 91.1% had the chronic form of the disease and 8.8% had an acute form. In this study, 52% of patients had concomitant diseases with PCM, of whom 28.5% had tuberculosis. Outcomes of cases showed that 14.7% of patients died, 22.5% were discharged from outpatient treatment and 12.7% continued treatment. Regarding the death rate, the results reflect index of 10 deaths per million of inhabitant per year. Conclusion: The data indicate that the micro-region bordering the Itaipu Lake is an endemic area for PCM and has high death rates among these patients.

Keyword: Paracoccidioidomycosis, Paracoccidioides brasiliensis, Itaipu Lake, Mortality, Mycosis

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